Drug Information

Drug General Information
Drug ID
D0X3ST
Former ID
DNC003480
Drug Name
Icrf-187
Drug Type
Small molecular drug
Indication Chemoprotection [ICD9: 191; ICD10:C71] Approved [544735], [551871]
Structure
Download
2D MOL

3D MOL
Formula
C11H16N4O4
Canonical SMILES
CC(CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2
InChI
1S/C11H16N4O4/c1-7(15-5-10(18)13-11(19)6-15)2-14-3-8(16)12-9(17)4-14/h7H,2-6H2,1H3,(H,12,16,17)(H,13,18,19)/t7-/m0/s1
InChIKey
BMKDZUISNHGIBY-ZETCQYMHSA-N
CAS Number
CAS 24584-09-6
PubChem Compound ID
71384
PubChem Substance ID
442425, 831389, 8194593, 11405762, 14774896, 14872576, 17397819, 43127718, 46505982, 46506541, 50012896, 50139412, 57318172, 75683665, 93166226, 93619796, 103693192, 104350333, 117600767, 126670108, 127536650, 131307062, 134337939, 135029834, 136376430, 137002682, 137241718, 141868796, 144205809, 152035811, 160812421, 160871504, 160963727, 162174646, 163089322, 170464709, 172080045, 172092159, 172860861, 174007392, 174476563, 174560588, 175266611, 176484596, 176484943, 177748989, 178103902, 179117166, 184816244, 198945773
Target and Pathway
Target(s) DNA topoisomerase II, beta isozyme Target Info Inhibitor [551393]
PANTHER Pathway DNA replication
References
Ref 544735Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000788)
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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