Drug Information

Drug General Information
Drug ID
D0X5SD
Former ID
DAP000012
Drug Name
Disulfiram
Synonyms
Abstenisil; Abstensil; Abstinil; Abstinyl; Alcophobin; Antabus; Antabuse; Antadix; Antaenyl; Antaethan; Antaethyl; Antaetil; Antalcol; Antetan; Antethyl; Antetil; Anteyl; Anthethyl; Antiaethan; Anticol; Antietanol; Antiethanol; Antietil; Antikol; Antivitium; Aversan; Averzan; Bonibal; Contralin; Contrapot; Cronetal; Dicupral; Disetil; Disulfan; Disulfirame; Disulfiramo; Disulfiramum; Disulfirm; Disulfram; Disulfuram; Disulphuram; Ephorran; Espenal; Esperal; Etabus; Ethyldithiourame; Ethyldithiurame; Exhoran; Exhorran; Gababentin; Hoca; Krotenal; Nocbin; Nocceler; Noxal; Refusal; Stopaethyl; Stopethyl; Stopety; Stopetyl; TATD; TETD; THIOCID; TTD; TTS; Tenurid; Tenutex; Tetidis; Tetradin; Tetradine; Tetraethylthiuram; Tetraetil; Teturam; Teturamin; Thireranide; Thiuranide; Tillram; Tiuram; Accel TET; Akrochem TETD; Ancazide ET; Antab use; Disulfirame [DCIT]; Ekagom DTET; Ekagom TEDS; Ekagom TETDS; Ekaland TETD; Esperal [France]; Eta bus; Ethyl Thiram; Ethyl Thiudad; Ethyl Thiurad; Ethyl Tuads Rodform; Ethyl Tuex; Ethyl tuads; Etyl Tuex; Nocceler TET; Perkacit TETD; Perkait TETD; Robac TET; Sanceler TET; Soxinol TET; TTS x; Tet raethylthiuram; Thiuram E; Dupon 4472; T 1132; Accel TET-R; Alk-aubs; Antabus (TN); Antabuse (TN); Anti-ethyl; Antivitium (Spain); ENT 27,340; Nocceler TET-G; Noxal (VAN); Ro-sulfiram; Sanceler TET-G; Tuads, ethyl; Usaf B-33; Ro-Sulfram-500 (USA)
Drug Type
Small molecular drug
Indication Alcohol use disorders [ICD9: 303; ICD10:F10.2] Approved [536276], [542177]
Therapeutic Class
Alcohol Deterrents
Company
Odyssey Pharmaceuticals
Structure
Download
2D MOL

3D MOL
Formula
C10H20N2S4
InChI
InChI=1S/C10H20N2S4/c1-5-11(6-2)9(13)15-16-10(14)12(7-3)8-4/h5-8H2,1-4H3
InChIKey
AUZONCFQVSMFAP-UHFFFAOYSA-N
CAS Number
CAS 97-77-8
PubChem Compound ID
3117
PubChem Substance ID
4833, 86944, 604564, 841760, 3134612, 7343344, 7847199, 8151985, 10321282, 10538921, 11111859, 11111860, 11363904, 11366466, 11369028, 11371250, 11374034, 11377190, 11466125, 11467245, 11484927, 11485729, 11488992, 11490221, 11492043, 11494824, 11533044, 11533307, 14720391, 14751553, 17405720, 22390447, 22391499, 24278722, 24888757, 26611716, 26680072, 26719650, 26747681, 26747682, 26753660, 26753661, 29222259, 46386898, 46487911, 46506008, 47216881, 47736606, 47810875, 48110561
ChEBI ID
ChEBI:4659
SuperDrug ATC ID
N07BB01; P03AA04
SuperDrug CAS ID
cas=000097778
Target and Pathway
Target(s) Aldehyde dehydrogenase Target Info Inhibitor [536206]
References
Ref 536276Choosing the right medication for the treatment of alcoholism. Curr Psychiatry Rep. 2006 Oct;8(5):383-8.
Ref 542177(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7168).
Ref 536206Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms. Pharmacol Ther. 2006 Sep;111(3):855-76. Epub 2006 Mar 20.

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