Drug General Information
Drug ID
D0X7SR
Former ID
DNC008650
Drug Name
8-prenylapigenin
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529676]
Structure
Download
2D MOL

3D MOL

Formula
C20H18O5
Canonical SMILES
CC(=CCC1=C(C=C(C2=C1OC(=CC2=O)C3=CC=C(C=C3)O)O)O)C
InChI
1S/C20H18O5/c1-11(2)3-8-14-15(22)9-16(23)19-17(24)10-18(25-20(14)19)12-4-6-13(21)7-5-12/h3-7,9-10,21-23H,8H2,1-2H3
InChIKey
MEHHCBRCXIDGKZ-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) CGMP-specific 3',5'-cyclic phosphodiesterase Target Info Inhibitor [529676]
KEGG Pathway Purine metabolism
cGMP-PKG signaling pathway
NetPath Pathway TGF_beta_Receptor Signaling Pathway
Reactome cGMP effects
References
Ref 529676J Nat Prod. 2008 Sep;71(9):1513-7. Epub 2008 Sep 9.Potent inhibition of human phosphodiesterase-5 by icariin derivatives.
Ref 529676J Nat Prod. 2008 Sep;71(9):1513-7. Epub 2008 Sep 9.Potent inhibition of human phosphodiesterase-5 by icariin derivatives.

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