Drug General Information
Drug ID	D0XH2N
Former ID	DIB004739
Drug Name	RS-1748
Indication	Asthma [ICD10:J45]		Investigative	[543896]
Company	Daiichi Sankyo Co Ltd
Structure		Download 2D MOL 3D MOL
Canonical SMILES	c1(nc(c(cn1)F)NCc1c(cc(cc1)F)F)c1ccc(cc1)OCCN(CC)CC
Target and Pathway
Target(s)	C-Cchemokine receptor type 4	Target Info	Modulator	[543896]
KEGG Pathway	Cytokine-cytokine receptor interaction
	Chemokine signaling pathway
	Viral carcinogenesis
PANTHER Pathway	Inflammation mediated by chemokine and cytokine signaling pathway
Reactome	Chemokine receptors bind chemokines
	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 543896	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 61).
Ref 543896	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 61).

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