Drug General Information
Drug ID	D0XW6Y
Former ID	DIB004474
Drug Name	S-38093
Synonyms	S-41150; S-38471-1; S-750-1; Histamine H3 antagonists (sleep/cognitive disorders), Servier
Indication	Alzheimer disease [ICD9: 331; ICD10:G30]		Phase 2	[549097]
Company	Servier
Structure		Download 2D MOL 3D MOL
Canonical SMILES	C1CCN2C(C1)CN(CC2)CCCCOc1ccc(cc1)C(=O)c1ccc(cc1)/C(=N/O<br />)/C
Target and Pathway
Target(s)	Histamine H3 receptor	Target Info	Antagonist	[549954]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
	G alpha (i) signalling events
WikiPathways	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 549097	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800032202)
Ref 549954	Histamine H3 Receptors and Sleep-Wake Regulation. JPET January 2011 vol. 336 no. 1 17-23.

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