Drug General Information
Drug ID	D0Y0GG
Former ID	DIB016370
Drug Name	Epanolol
Synonyms	Visacor; TS-704
Drug Type	Small molecular drug
Indication	Angina pectoris [ICD9: 413; ICD10:I20]		Discontinued in Preregistration	[544649]
Company	Imperial Chemical Industries Plc
Structure		Download 2D MOL 3D MOL
Formula	C20H23N3O4
Canonical SMILES	N#Cc1c(OCC(O)CNCCNC(=O)Cc2ccc(cc2)O)cccc1
CAS Number	CAS 86880-51-5
PubChem Compound ID	72014
Target and Pathway
Target(s)	Beta-3 adrenergic receptor	Target Info	Modulator	[530320]
KEGG Pathway	Calcium signaling pathway
	cGMP-PKG signaling pathway
	Neuroactive ligand-receptor interaction
	Endocytosis
	Salivary secretion
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
	Beta3 adrenergic receptor signaling pathway
Reactome	Adrenoceptors
	G alpha (s) signalling events
WikiPathways	Monoamine GPCRs
	Calcium Regulation in the Cardiac Cell
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 544649	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000427)
Ref 530320	Pharmacokinetics of epanolol after acute and chronic oral dosing in elderly patients with stable angina pectoris. Br J Clin Pharmacol. 1990 Mar;29(3):333-7.

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