Drug Information

Drug General Information
Drug ID
D0Y2XZ
Former ID
DIB015395
Drug Name
MK-4166
Drug Type
Antibody
Indication Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] Phase 1 [524744]
Company
Merck
Target and Pathway
Target(s) Activation-inducible TNFR family receptor Target Info [525419]
KEGG Pathway Cytokine-cytokine receptor interaction
NetPath Pathway TCR Signaling Pathway
Pathway Interaction Database Downstream signaling in na&#xef
Reactome TNFs bind their physiological receptors
References
Ref 524744ClinicalTrials.gov (NCT02132754) Study of MK-4166 in Participants With Advanced Solid Tumors (MK-4166-001). U.S. National Institutes of Health.
Ref 525419Immuno-oncology moves beyond PD-1. Nat Biotechnol. 2015 Jul;33(7):673-5. doi: 10.1038/nbt0715-673.

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