Drug Information

Drug General Information
Drug ID
D0Y3LJ
Former ID
DCL000471
Drug Name
AZD5904
Drug Type
Small molecular drug
Indication Chronic obstructive pulmonary disease; Multiple scierosis [ICD9: 490-492, 494-496, 340; ICD10:J40-J44, J47, G35] Discontinued in Phase 1 [542698], [548327]
Company
AstraZeneca
Structure
Download
2D MOL

3D MOL
Formula
C10H12N4O2S
InChI
InChI=1S/C10H12N4O2S/c15-9-7-8(12-5-11-7)14(10(17)13-9)4-6-2-1-3-16-6/h5-6H,1-4H2,(H,11,12)(H,13,15,17)/t6-/m1/s1
InChIKey
RSPDBEVKURKEII-ZCFIWIBFSA-N
PubChem Compound ID
10264211
PubChem Substance ID
15268512, 41249446, 75641436, 80954492, 144240094, 160844966, 223366061, 228411217, 247063637
Target and Pathway
Target(s) Myeloperoxidase Target Info Inhibitor [550288]
KEGG Pathway Phagosome
Transcriptional misregulation in cancer
Pathway Interaction Database C-MYB transcription factor network
IL23-mediated signaling events
WikiPathways Folate Metabolism
Vitamin B12 Metabolism
Selenium Micronutrient Network
References
Ref 542698(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7728).
Ref 548327Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024670)
Ref 550288Clinical pipeline report, company report or official report of AstraZeneca (2009).

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