Drug General Information
Drug ID	D0Y4OI
Former ID	DIB000582
Drug Name	SKF-105809
Synonyms	SKF-105561
Drug Type	Small molecular drug
Indication	Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89]		Phase 1	[529852]
Company	SmithKline Beecham plc
Structure		Download 2D MOL 3D MOL
Formula	C18H17N3OS
CAS Number	CAS 122454-69-7
PubChem Compound ID	129725
Target and Pathway
Target(s)	Cyclooxygenase	Target Info	Modulator	[529852]
	Arachidonate 5-lipoxygenase	Target Info	Inhibitor	[529852]
BioCyc Pathway	Aspirin-triggered lipoxin biosynthesis
	Resolvin D biosynthesis
	Leukotriene biosynthesis
	Lipoxin biosynthesis
	Aspirin triggered resolvin D biosynthesis
	Aspirin triggered resolvin E biosynthesis
KEGG Pathway	Arachidonic acid metabolism
	Metabolic pathways
	Serotonergic synapse
	Ovarian steroidogenesis
	Toxoplasmosis
NetPath Pathway	IL4 Signaling Pathway
PathWhiz Pathway	Arachidonic Acid Metabolism
WikiPathways	Vitamin D Receptor Pathway
	Arachidonic acid metabolism
	Eicosanoid Synthesis
	Selenium Micronutrient Network
References
Ref 529852	Analgetic activity of SK&F 105809, a dual inhibitor of arachidonic acid metabolism. Agents Actions Suppl. 1991;32:113-7.
Ref 529852	Analgetic activity of SK&F 105809, a dual inhibitor of arachidonic acid metabolism. Agents Actions Suppl. 1991;32:113-7.

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