Drug Information
Drug General Information | |||||
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Drug ID |
D0Y5JC
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Former ID |
DNAP001693
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Drug Name |
Avanafil
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Synonyms |
Stendra (TN)
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Drug Type |
Small molecular drug
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Company |
Vivus
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Structure |
Download2D MOL |
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Formula |
C23H26ClN7O3
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InChI |
InChI=1S/C23H26ClN7O3/c1-34-19-6-5-15(10-18(19)24)11-27-21-17(22(33)28-13-20-25-7-3-8-26-20)12-29-23(30-21)31-9-2-4-16(31)14-32/h3,5-8,10,12,16,32H,2,4,9,11,13-14H2,1H3,(H,28,33)(H,27,29,30)/t16-/m0/s1
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InChIKey |
WEAJZXNPAWBCOA-INIZCTEOSA-N
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CAS Number |
CAS 330784-47-9
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PubChem Compound ID | |||||
PubChem Substance ID |
14834924, 15132057, 17397370, 24160918, 45292193, 50284293, 57373612, 125299302, 126680642, 135264773, 136922931, 137082779, 137263447, 143177981, 160645587, 162255031, 164178031, 164194088, 164835991, 165222624, 165245576, 170502146, 174528935, 175267514, 175427065, 178104020, 185997047, 189480340, 198993783, 210275731, 210281392, 223635467, 223667975, 223700581, 223797060, 226490661, 241381281, 244115505, 249855750, 250163172, 250224291, 252066590, 252214915, 252436466
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ChEBI ID |
ChEBI:66876
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Target and Pathway | |||||
Target(s) | CGMP-specific 3',5'-cyclic phosphodiesterase | Target Info | Modulator | [551871] | |
KEGG Pathway | Purine metabolism | ||||
cGMP-PKG signaling pathway | |||||
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
Reactome | cGMP effects | ||||
References | |||||
Ref 532210 | Nat Rev Drug Discov. 2013 Feb;12(2):87-90. | ||||
Ref 542472 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7448). |
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