Drug General Information
Drug ID
D0Y5JC
Former ID
DNAP001693
Drug Name
Avanafil
Synonyms
Stendra (TN)
Drug Type
Small molecular drug
Indication Erectile dysfunction [ICD9: 302.72, 607.84; ICD10:F52.2, N48.4] Approved [532210], [542472]
Company
Vivus
Structure
Download
2D MOL

3D MOL

Formula
C23H26ClN7O3
InChI
InChI=1S/C23H26ClN7O3/c1-34-19-6-5-15(10-18(19)24)11-27-21-17(22(33)28-13-20-25-7-3-8-26-20)12-29-23(30-21)31-9-2-4-16(31)14-32/h3,5-8,10,12,16,32H,2,4,9,11,13-14H2,1H3,(H,28,33)(H,27,29,30)/t16-/m0/s1
InChIKey
WEAJZXNPAWBCOA-INIZCTEOSA-N
CAS Number
CAS 330784-47-9
PubChem Compound ID
PubChem Substance ID
ChEBI ID
ChEBI:66876
Target and Pathway
Target(s) CGMP-specific 3',5'-cyclic phosphodiesterase Target Info Modulator [551871]
KEGG Pathway Purine metabolism
cGMP-PKG signaling pathway
NetPath Pathway TGF_beta_Receptor Signaling Pathway
Reactome cGMP effects
References
Ref 532210Nat Rev Drug Discov. 2013 Feb;12(2):87-90.
Ref 542472(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7448).
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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