Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0YB4D
|
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| Former ID |
DIB010408
|
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| Drug Name |
Eldacimibe
|
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| Synonyms |
ACA-147; WAY-ACA-147
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| Drug Type |
Small molecular drug
|
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| Indication | Hyperlipidaemia [ICD9: 272.0-272.4; ICD10:E78] | Phase 2 | [1] | ||
| Company |
Wyeth
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C39H58N2O5
|
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| Canonical SMILES |
C1(=C(N(Cc2ccc(CC(C)(C)C)cc2)CCCCCC)Nc2cc(c(c(C(C)(C)C)<br />c2)O)C(C)(C)C)C(=O)OC(OC1=O)(C)C
|
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| CAS Number |
CAS 141993-70-6
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Liver carboxylesterase | Target Info | Modulator | [2] | |
| KEGG Pathway | Drug metabolism - other enzymes | ||||
| Metabolic pathways | |||||
| Pathway Interaction Database | E2F transcription factor network | ||||
| WikiPathways | NRF2 pathway | ||||
| Nuclear Receptors Meta-Pathway | |||||
| Heroin metabolism | |||||
| Irinotecan Pathway | |||||
| Fluoropyrimidine Activity | |||||
| Phase I biotransformations, non P450 | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003592) | ||||
| REF 2 | Prospects for drug therapy for hyperlipoproteinaemia. Diabete Metab. 1995 Apr;21(2):139-46. | ||||
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