Drug General Information
Drug ID
D0YC1I
Former ID
DNC001251
Drug Name
S-(-)-Lisuride
Drug Type
Small molecular drug
Indication Discovery agent Investigative [535914]
Structure
Download
2D MOL

3D MOL

Formula
C20H26N4O
Canonical SMILES
CCN(CC)C(=O)NC1CN(C2CC3=CNC4=CC=CC(=C34)C2=C1)C
InChI
1S/C20H26N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14/h6-8,10-11,14,18,21H,4-5,9,12H2,1-3H3,(H,22,25)/t14-,18-/m1/s1
InChIKey
BKRGVLQUQGGVSM-RDTXWAMCSA-N
CAS Number
CAS 140387-89-9
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
G02CB02
SuperDrug CAS ID
cas=018016803
Target and Pathway
Target(s) Histamine H1 receptor Target Info Agonist [535914]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
PANTHER Pathway Histamine H1 receptor mediated signaling pathway
Reactome Histamine receptors
G alpha (q) signalling events
WikiPathways Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
IL-4 Signaling Pathway
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 5359148R-lisuride is a potent stereospecific histamine H1-receptor partial agonist. Mol Pharmacol. 2004 Mar;65(3):538-49.
Ref 5359148R-lisuride is a potent stereospecific histamine H1-receptor partial agonist. Mol Pharmacol. 2004 Mar;65(3):538-49.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.