Drug General Information
Drug ID
D0YC1R
Former ID
DIB010712
Drug Name
BMS-520
Synonyms
BMS-520; S1P1 agonists (immunology); S1P1 agonists (immunology), Bristol-Myers Squibb
Indication Immune disorder [ICD10:D80-D89] Investigative [543701]
Company
Bristol-Myers Squibb Co
Structure
Download
2D MOL

3D MOL

Canonical SMILES
FC(F)(c1c(c2ccccc2)noc1c1onc(c2ccc(CN3CC(C3)C(=O)O)cc2)<br />n1)F
Target and Pathway
Target(s) Sphingosine 1-phosphate receptor 1 Target Info Agonist [543701]
KEGG Pathway FoxO signaling pathway
Sphingolipid signaling pathway
Neuroactive ligand-receptor interaction
NetPath Pathway IL4 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
IL2 Signaling Pathway
Pathway Interaction Database Fc-epsilon receptor I signaling in mast cells
S1P3 pathway
S1P1 pathway
Sphingosine 1-phosphate (S1P) pathway
PDGFR-beta signaling pathway
Reactome G alpha (i) signalling events
Lysosphingolipid and LPA receptors
WikiPathways Signal Transduction of S1P Receptor
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 543701(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 275).
Ref 543701(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 275).

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