TTD | Drug: D0YJ5H

Drug General Information
Drug ID	D0YJ5H
Former ID	DIB001646
Drug Name	EX-1311
Synonyms	EX-1311; EX-1350; EX-1365; EX-1832; EX-51; Ghrelin antagonists (metabolic disease); Ghrelin antagonists (metabolic disease), Elixir; Ghrelin antagonists (metabolic disease), Elixir/Novartis
Indication	Metabolic disorders [ICD9: 270-279; ICD10:E70-E89]		Investigative	[543633]
Company	Elixir Pharmaceuticals Inc
Structure		Download 2D MOL 3D MOL
Canonical SMILES	C(CCN(CC)CC)S(=O)(=O)N[C@H](CCc1ccccc1)c1[nH]nc(n1)c1cc<br />c(cc1)OC
Target and Pathway
Target(s)	Growth hormone secretagogue receptor type 1	Target Info	Antagonist	[543633]
KEGG Pathway	cAMP signaling pathway
KEGG Pathway	Neuroactive ligand-receptor interaction
NetPath Pathway	Leptin Signaling Pathway
Reactome	Peptide ligand-binding receptors
Reactome	G alpha (q) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 543633	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 246).
Ref 543633	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 246).

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information