Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0YQ7U
|
||||
| Former ID |
DNCL002981
|
||||
| Drug Name |
Cenicriviroc
|
||||
| Drug Type |
Small molecular drug
|
||||
| Company |
Tobira Therapeutics
|
||||
| Structure |
|
Download2D MOL |
|||
| Formula |
C41H52N4O4S
|
||||
| InChI |
InChI=1S/C41H52N4O4S/c1-5-7-22-48-23-24-49-38-15-10-32(11-16-38)33-12-19-40-35(25-33)26-34(9-8-21-44(40)28-31(3)4)41(46)43-36-13-17-39(18-14-36)50(47)29-37-27-42-30-45(37)20-6-2/h10-19,25-27,30-31H,5-9,20-24,28-29H2,1-4H3,(H,43,46)/b34-26+/t50-/m0/s1
|
||||
| InChIKey |
PNDKCRDVVKJPKG-WHERJAGFSA-N
|
||||
| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | C-C chemokinereceptor type 5 | Target Info | Modulator | [533043] | |
| Pathway Interaction Database | IL12-mediated signaling events | ||||
| References | |||||
| Ref 533043 | The dual CCR5 and CCR2 inhibitor cenicriviroc does not redistribute HIV into extracellular space: implications for plasma viral load and intracellular DNA decline. J Antimicrob Chemother. 2015 Mar;70(3):750-6. | ||||
| Ref 542922 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 801). | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.