Drug General Information
Drug ID
D0Z1XE
Former ID
DNC008380
Drug Name
JWH-324
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531027]
Structure
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2D MOL

3D MOL

Formula
C21H34O
Canonical SMILES
CCCCCCC(C)(C)C1=CC=C(C=C1)C2CCCC(C2)O
InChI
1S/C21H34O/c1-4-5-6-7-15-21(2,3)19-13-11-17(12-14-19)18-9-8-10-20(22)16-18/h11-14,18,20,22H,4-10,15-16H2,1-3H3/t18-,20+/m0/s1
InChIKey
CICRJVLFNFCUOX-AZUAARDMSA-N
PubChem Compound ID
Target and Pathway
Target(s) Cannabinoid receptor 1 Target Info Inhibitor [531027]
Cannabinoid receptor 2 Target Info Inhibitor [531027]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signalinghsa04080:Neuroactive ligand-receptor interaction
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling eventsR-HSA-373076:Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
BDNF signaling pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 531027Bioorg Med Chem. 2010 Aug 1;18(15):5475-82. Epub 2010 Jun 22.Synthesis and pharmacology of 1-methoxy analogs of CP-47,497.
Ref 531027Bioorg Med Chem. 2010 Aug 1;18(15):5475-82. Epub 2010 Jun 22.Synthesis and pharmacology of 1-methoxy analogs of CP-47,497.

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