Drug Information

Drug General Information
Drug ID
D0Z7FY
Former ID
DIB009835
Drug Name
CEM-301
Synonyms
CEM-301; Macrolide motilin agonists, Optimer/Cempra
Indication Gastric motility disorder [ICD10:K22.4] Investigative [543753]
Company
Cempra Pharmaceuticals Inc
Target and Pathway
Target(s) Motilin receptor Target Info Agonist [543753]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 543753(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 297).
Ref 543753(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 297).

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