Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0Z7TM
|
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| Former ID |
DNC008462
|
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| Drug Name |
BMS-645737
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [529409] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C20H20N8O
|
||||
| Canonical SMILES |
CC1=CC2=CC(=CN=C2N1)NC3=NC=NN4C3=C(C(=C4)C5=NN=C(O5)C)C<br />(C)C
|
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| InChI |
1S/C20H20N8O/c1-10(2)16-15(20-27-26-12(4)29-20)8-28-17(16)19(22-9-23-28)25-14-6-13-5-11(3)24-18(13)21-7-14/h5-10H,1-4H3,(H,21,24)(H,22,23,25)
|
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| InChIKey |
OOQXPATWSOGSAV-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | Inhibitor | [529409] | |
| Potassium voltage-gated channel subfamily H member 2 | Target Info | Inhibitor | [529409] | ||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathway | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY network | |||||
| PathWhiz Pathway | Muscle/Heart Contraction | ||||
| References | |||||
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