Drug Information

Drug General Information
Drug ID
D0Z7ZM
Former ID
DCL000953
Drug Name
Rhucin
Synonyms
Rhucin (TN)
Drug Type
Small molecular drug
Indication Hereditary angioedema [ICD9: 277.6; ICD10:D84.1] Approved [531351], [532027]
Company
Pfizer
Structure
Download
2D MOL

3D MOL
Formula
C22H30N6O4S
Canonical SMILES
CCCC1=NN(C2=C1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC<br />4)C)OCC)C
InChI
1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)
InChIKey
BNRNXUUZRGQAQC-UHFFFAOYSA-N
PubChem Compound ID
5212
PubChem Substance ID
9468, 585744, 832888, 4075716, 4368414, 4980084, 7980598, 8153203, 11342069, 11362252, 11364449, 11367011, 11369573, 11373023, 11374191, 11377735, 11485511, 11487654, 11489464, 11491707, 11492401, 11495369, 11528697, 14834479, 14883184, 26612617, 26680877, 26748898, 26748899, 29215463, 29224269, 46393303, 46393579, 46394222, 46508371, 46514731, 47810856, 48259349, 48416538, 50085897, 50416042, 53786977, 56313704, 56322606, 57322656, 61212546, 81040866, 85248200, 85788522, 89736128
Target and Pathway
Target(s) C1 esterase inhibitor Target Info Modulator [531351], [532027]
References
Ref 531351Mullard A: 2010 FDA drug approvals. Nat Rev Drug Discov. 2011 Feb;10(2):82-5.
Ref 532027Recombinant human c1 inhibitor (conestat alfa): in the treatment of angioedema attacks in hereditary angioedema. BioDrugs. 2012 Oct 1;26(5):315-23.
Ref 531351Mullard A: 2010 FDA drug approvals. Nat Rev Drug Discov. 2011 Feb;10(2):82-5.
Ref 532027Recombinant human c1 inhibitor (conestat alfa): in the treatment of angioedema attacks in hereditary angioedema. BioDrugs. 2012 Oct 1;26(5):315-23.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.