Drug General Information
Drug ID
D0ZO8Z
Former ID
DNC006684
Drug Name
2-(3,4-dimethoxybenzamido)thiophene-3-carboxamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528114]
Structure
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2D MOL

3D MOL

Formula
C14H14N2O4S
Canonical SMILES
COC1=C(C=C(C=C1)C(=O)NC2=C(C=CS2)C(=O)N)OC
InChI
1S/C14H14N2O4S/c1-19-10-4-3-8(7-11(10)20-2)13(18)16-14-9(12(15)17)5-6-21-14/h3-7H,1-2H3,(H2,15,17)(H,16,18)
InChIKey
LORRZRFBMUDPOE-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) FL cytokine receptor Target Info Inhibitor [528114]
KEGG Pathway Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
Pathways in cancer
Transcriptional misregulation in cancer
Acute myeloid leukemia
Central carbon metabolism in cancer
References
Ref 528114Bioorg Med Chem Lett. 2006 Jun 15;16(12):3282-6. Epub 2006 Mar 31.Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3.
Ref 528114Bioorg Med Chem Lett. 2006 Jun 15;16(12):3282-6. Epub 2006 Mar 31.Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3.

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