Drug General Information
Drug ID	D0ZX0Y
Former ID	DNC007846
Drug Name	4-hexylphenyl propiolate
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529081]
Structure		Download 2D MOL 3D MOL
Formula	C15H18O2
Canonical SMILES	CCCCCCC1=CC=C(C=C1)OC(=O)C#C
InChI	1S/C15H18O2/c1-3-5-6-7-8-13-9-11-14(12-10-13)17-15(16)4-2/h2,9-12H,3,5-8H2,1H3
InChIKey	IAEVDNHEIHTNJR-UHFFFAOYSA-N
PubChem Compound ID	23635856
Target and Pathway
Target(s)	Thyroid hormone receptor beta-1	Target Info	Inhibitor	[529081]
	Thyroid hormone receptor alpha	Target Info	Inhibitor	[529081]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Thyroid hormone signaling pathwayhsa04080:Neuroactive ligand-receptor interaction
	Thyroid hormone signaling pathway
Pathway Interaction Database	RXR and RAR heterodimerization with other nuclear receptorrxr_vdr_pathway:RXR and RAR heterodimerization with other nuclear receptor
Reactome	Nuclear Receptor transcription pathwayR-HSA-383280:Nuclear Receptor transcription pathway
WikiPathways	SIDS Susceptibility Pathways
	Hematopoietic Stem Cell Differentiation
	Nuclear ReceptorsWP474:Endochondral Ossification
	Nuclear Receptors
References
Ref 529081	J Med Chem. 2007 Nov 1;50(22):5269-80. Epub 2007 Oct 5.Inhibitors of the interaction of a thyroid hormone receptor and coactivators: preliminary structure-activity relationships.
Ref 529081	J Med Chem. 2007 Nov 1;50(22):5269-80. Epub 2007 Oct 5.Inhibitors of the interaction of a thyroid hormone receptor and coactivators: preliminary structure-activity relationships.

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