TTD | Drug: D0ZY9U

Drug General Information
Drug ID	D0ZY9U
Former ID	DIB012640
Drug Name	SLV-305
Indication	Gastric motility disorder [ICD10:K22.4]		Discontinued in Phase 2	[547249]
Company	Solvay SA
Target and Pathway
Target(s)	Motilin receptor	Target Info	Modulator	[543753]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Peptide ligand-binding receptors
Reactome	G alpha (q) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 547249	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800014470)
Ref 543753	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 297).

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Drug Information