Drug Information

Drug General Information
Drug ID
DX1IVA
Drug Name
1-[4-(8-Chloro-1-oxy-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-pyridin-4-yl-ethanone
Synonyms
CHEMBL341184
Indication Discovery agent Investigative [1587926]
Formula
C26H24ClN3O2
Canonical SMILES
[O-][n+]1cccc2CCc3cc(Cl)ccc3C(=C4CCN(CC4)C(=O)Cc5ccncc5)c12
InChI
InChI=1S/C26H24ClN3O2/c27-22-5-6-23-21(17-22)4-3-20-2-1-13-30(32)26(20)25(23)19-9-14-29(15-10-19)24(31)16-18-7-11-28-12-8-18/h1-2,5-8,11-13,17H,3-4,9-10,14-16H2
InChIKey
YMDVWHNMIAFIIQ-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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