Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX2PII
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| Drug Name |
(S)-3-Methyl-2-(naphthalene-1-sulfonylamino)-pentanoic acid [(S)-1-formyl-2-(1H-indol-2-yl)-ethyl]-amide
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| Synonyms |
CHEMBL197958
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H29N3O4S
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| Canonical SMILES |
CCC(C)[C@H](NS(=O)(=O)c1cccc2ccccc12)C(=O)N[C@@H](Cc3cc4ccccc4[nH]3)C=O
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| InChI |
InChI=1S/C27H29N3O4S/c1-3-18(2)26(30-35(33,34)25-14-8-11-19-9-4-6-12-23(19)25)27(32)29-22(17-31)16-21-15-20-10-5-7-13-24(20)28-21/h4-15,17-18,22,26,28,30H,3,16H2,1-2H3,(H,29,32)/t18?,22-,26-/m0/s1
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| InChIKey |
LBJZOWAHNPGWGP-CZOSNNJRSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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