Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX3GFO
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| Drug Name |
N-((S)-3-cyclohexyl-1-oxo-1-(2-(4-(trifluoromethoxy)phenylamino)ethylamino)propan-2-yl)-5-(3-(trifluoromethyl)phenyl)furan-2-carboxamide
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| Synonyms |
CHEMBL385912
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C30H31F6N3O4
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| Canonical SMILES |
FC(F)(F)Oc1ccc(NCCNC(=O)[C@H](CC2CCCCC2)NC(=O)c3oc(cc3)c4cccc(c4)C(F)(F)F)cc1
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| InChI |
InChI=1S/C30H31F6N3O4/c31-29(32,33)21-8-4-7-20(18-21)25-13-14-26(42-25)28(41)39-24(17-19-5-2-1-3-6-19)27(40)38-16-15-37-22-9-11-23(12-10-22)43-30(34,35)36/h4,7-14,18-19,24,37H,1-3,5-6,15-17H2,(H,38,40)(H,39,41)/t24-/m0/s1
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| InChIKey |
QNYDUYVPWWZGBS-DEOSSOPVSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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