Drug Information
| Drug General Information | |||||
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| Drug ID |
DX3HVS
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| Drug Name |
N-((S)-3-cyclohexyl-1-((S)-4-(methylsulfonyl)-1-(4-(trifluoromethoxy)phenylamino)butan-2-ylamino)-1-oxopropan-2-yl)morpholine-4-carboxamide
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| Synonyms |
CHEMBL379079
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C26H39F3N4O6S
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| Canonical SMILES |
CS(=O)(=O)CC[C@@H](CNc1ccc(OC(F)(F)F)cc1)NC(=O)[C@H](CC2CCCCC2)NC(=O)N3CCOCC3
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| InChI |
InChI=1S/C26H39F3N4O6S/c1-40(36,37)16-11-21(18-30-20-7-9-22(10-8-20)39-26(27,28)29)31-24(34)23(17-19-5-3-2-4-6-19)32-25(35)33-12-14-38-15-13-33/h7-10,19,21,23,30H,2-6,11-18H2,1H3,(H,31,34)(H,32,35)/t21-,23-/m0/s1
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| InChIKey |
LIZMSGSZTVNLRI-GMAHTHKFSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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