Drug Information

Drug General Information
Drug ID
DX4SJM
Drug Name
4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1-carboxylic acid (1-oxy-pyridin-4-yl)-amide
Synonyms
CHEMBL170887
Indication Discovery agent Investigative [1587926]
Formula
C24H23BrClN5O2
Canonical SMILES
[O-][n+]1ccc(NC(=O)N2CCN(CC2)C3c4ccc(Cl)cc4CCc5cc(Br)cnc35)cc1
InChI
InChI=1S/C24H23BrClN5O2/c25-18-13-17-2-1-16-14-19(26)3-4-21(16)23(22(17)27-15-18)29-9-11-30(12-10-29)24(32)28-20-5-7-31(33)8-6-20/h3-8,13-15,23H,1-2,9-12H2,(H,28,32)
InChIKey
JTMOULOSRHDSIC-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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