Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX5H4O
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| Drug Name |
2-Cyano-4-[(spiro[2.5]oct-6-ylmethyl)-amino]-pyrimidine-5-carboxylic acid ((S)-1-benzyl-2-pyrrolidin-1-yl-ethyl)-amide
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| Synonyms |
CHEMBL509262
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H36N6O
|
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| Canonical SMILES |
O=C(N[C@H](CN1CCCC1)Cc2ccccc2)c3cnc(nc3NCC4CCC5(CC4)CC5)C#N
|
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| InChI |
InChI=1S/C28H36N6O/c29-17-25-30-19-24(26(33-25)31-18-22-8-10-28(11-9-22)12-13-28)27(35)32-23(20-34-14-4-5-15-34)16-21-6-2-1-3-7-21/h1-3,6-7,19,22-23H,4-5,8-16,18,20H2,(H,32,35)(H,30,31,33)/t23-/m0/s1
|
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| InChIKey |
ZFWPNYQSYFERIU-QHCPKHFHSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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