Drug Information

Drug General Information
Drug ID
DX6MWL
Drug Name
4-{2-[4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-oxo-ethyl}-piperidine-1-carboxylic acid propylamide
Synonyms
CHEMBL172097
Indication Discovery agent Investigative [1587926]
Formula
C29H37BrClN5O2
Canonical SMILES
CCCNC(=O)N1CCC(CC(=O)N2CCN(CC2)C3c4ccc(Cl)cc4CCc5cc(Br)cnc35)CC1
InChI
InChI=1S/C29H37BrClN5O2/c1-2-9-32-29(38)36-10-7-20(8-11-36)16-26(37)34-12-14-35(15-13-34)28-25-6-5-24(31)18-21(25)3-4-22-17-23(30)19-33-27(22)28/h5-6,17-20,28H,2-4,7-16H2,1H3,(H,32,38)
InChIKey
NGSYGMDRTBHHQI-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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