Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX8QK5
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| Drug Name |
4-[2-(1-Methyl-piperidin-4-yl)-ethoxy]-6-[(spiro[2.5]oct-6-ylmethyl)-amino]-pyrimidine-2-carbonitrile
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| Synonyms |
CHEMBL496657
|
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C22H33N5O
|
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| Canonical SMILES |
CN1CCC(CCOc2cc(NCC3CCC4(CC3)CC4)nc(n2)C#N)CC1
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| InChI |
InChI=1S/C22H33N5O/c1-27-11-4-17(5-12-27)6-13-28-21-14-19(25-20(15-23)26-21)24-16-18-2-7-22(8-3-18)9-10-22/h14,17-18H,2-13,16H2,1H3,(H,24,25,26)
|
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| InChIKey |
IXULIQOVYWLEAV-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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