Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX9COK
|
||||
| Drug Name |
4-(1,4,7-Trioxa-10-aza-cyclododec-10-yl)-but-2-enoic acid [4-(4-benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide
|
||||
| Synonyms |
CHEMBL360211
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C37H40ClN5O6
|
||||
| Canonical SMILES |
CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccc4)c(Cl)c3)c2cc1NC(=O)\\C=C\\CN5CCOCCOCCOCC5
|
||||
| InChI |
InChI=1S/C37H40ClN5O6/c1-2-48-35-23-32-30(22-33(35)42-36(44)9-6-12-43-13-15-45-17-19-47-20-18-46-16-14-43)37(28(24-39)25-40-32)41-29-10-11-34(31(38)21-29)49-26-27-7-4-3-5-8-27/h3-11,21-23,25H,2,12-20,26H2,1H3,(H,40,41)(H,42,44)/b9-6+
|
||||
| InChIKey |
HBFLTOMPSWKWMR-RMKNXTFCSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Epidermal growth factor receptor III | Target Info | [1587926] | ||
| Receptor protein-tyrosine kinase erbB-2 | Target Info | [1587926] | |||
| KEGG Pathway | ErbB signaling pathway | ||||
| Calcium signaling pathway | |||||
| HIF-1 signaling pathway | |||||
| Focal adhesion | |||||
| Adherens junction | |||||
| Pathways in cancer | |||||
| Proteoglycans in cancer | |||||
| MicroRNAs in cancer | |||||
| Pancreatic cancer | |||||
| Endometrial cancer | |||||
| Prostate cancer | |||||
| Bladder cancer | |||||
| Non-small cell lung cancer | |||||
| Central carbon metabolism in cancer | |||||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | Cadherin signaling pathway | ||||
| EGF receptor signaling pathway | |||||
| PathWhiz Pathway | Phosphatidylinositol Phosphate Metabolism | ||||
| WikiPathways | DNA Damage Response (only ATM dependent) | ||||
| ErbB Signaling Pathway | |||||
| EGF/EGFR Signaling Pathway | |||||
| Focal Adhesion | |||||
| Extracellular vesicle-mediated signaling in recipient cells | |||||
| Bladder Cancer | |||||
| Signaling by ERBB2 | |||||
| Integrated Pancreatic Cancer Pathway | |||||
| Signaling Pathways in Glioblastoma | |||||
| Leptin signaling pathway | |||||
| miR-targeted genes in muscle cell - TarBase | |||||
| Semaphorin interactions | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.