Drug General Information |
Drug ID |
DXB5IC
|
Drug Name |
5-Hydroxy-2-(4-hydroxy-phenyl)-7-methoxy-benzofuran-4-carbonitrile
|
Synonyms |
CHEMBL187115
|
Indication |
Discovery agent
|
Investigative |
[1]
|
Formula |
C16H11NO4
|
Canonical SMILES |
COc1cc(O)c(C#N)c2cc(oc12)c3ccc(O)cc3
|
InChI |
InChI=1S/C16H11NO4/c1-20-15-7-13(19)12(8-17)11-6-14(21-16(11)15)9-2-4-10(18)5-3-9/h2-7,18-19H,1H3
|
InChIKey |
QHWZUEKEQMHGGA-UHFFFAOYSA-N
|
Target and Pathway |
Target(s) |
Estrogen receptor beta |
Target Info |
|
[1]
|
Estrogen receptor |
Target Info |
|
[1]
|
KEGG Pathway
|
Estrogen signaling pathway
|
Prolactin signaling pathwayhsa04915:Estrogen signaling pathway
|
Prolactin signaling pathway
|
Thyroid hormone signaling pathway
|
Endocrine and other factor-regulated calcium reabsorption
|
Proteoglycans in cancer
|
NetPath Pathway
|
FSH Signaling Pathway
|
EGFR1 Signaling Pathway
|
RANKL Signaling Pathway
|
Pathway Interaction Database
|
Plasma membrane estrogen receptor signaling
|
Validated nuclear estrogen receptor beta network
|
Validated nuclear estrogen receptor alpha networksmad2_3nuclearpathway:Regulation of nuclear SMAD2/3 signaling
|
Signaling events mediated by HDAC Class II
|
LKB1 signaling events
|
Regulation of Telomerase
|
ATF-2 transcription factor network
|
AP-1 transcription factor network
|
FOXM1 transcription factor network
|
Validated nuclear estrogen receptor alpha network
|
Signaling mediated by p38-alpha and p38-beta
|
FOXA1 transcription factor network
|
Reactome
|
Nuclear Receptor transcription pathwayR-HSA-1251985:Nuclear signaling by ERBB4
|
Nuclear Receptor transcription pathway
|
WikiPathways
|
SIDS Susceptibility Pathways
|
Ovarian Infertility Genes
|
Integrated Pancreatic Cancer Pathway
|
Nuclear ReceptorsWP712:Estrogen signaling pathway
|
Nuclear Receptors Meta-Pathway
|
Estrogen Receptor Pathway
|
Signaling by ERBB4
|
JAK/STAT
|
Leptin signaling pathway
|
miR-targeted genes in muscle cell - TarBase
|
Integrated Breast Cancer Pathway
|
Nuclear Receptors
|
References |
REF 1 | URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017 |