Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXB9IF
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| Drug Name |
(R,S)-4-methyl-2-[4'-(2-piperazin-1-yl-thiazol-4-yl)-biphenyl-3-yl]-pentanoic acid cyanomethyl-amide
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| Synonyms |
CHEMBL211737
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H31N5OS
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| Canonical SMILES |
CC(C)CC(C(=O)NCC#N)c1cccc(c1)c2ccc(cc2)c3csc(n3)N4CCNCC4
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| InChI |
InChI=1S/C27H31N5OS/c1-19(2)16-24(26(33)30-11-10-28)23-5-3-4-22(17-23)20-6-8-21(9-7-20)25-18-34-27(31-25)32-14-12-29-13-15-32/h3-9,17-19,24,29H,11-16H2,1-2H3,(H,30,33)
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| InChIKey |
BJXUTJHNAOJFQL-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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