Drug Information

Drug General Information
Drug ID
DXC1HO
Drug Name
Quinoline-3-carboxylic acid [1-(benzyl-methyl-carbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide
Synonyms
CHEMBL324760
Indication Discovery agent Investigative [1587926]
Formula
C29H26N4O2
Canonical SMILES
CN(Cc1ccccc1)C(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)c4cnc5ccccc5c4
InChI
InChI=1S/C29H26N4O2/c1-33(19-20-9-3-2-4-10-20)29(35)27(16-22-17-31-26-14-8-6-12-24(22)26)32-28(34)23-15-21-11-5-7-13-25(21)30-18-23/h2-15,17-18,27,31H,16,19H2,1H3,(H,32,34)/t27-/m1/s1
InChIKey
RTZSWSVEJWVMPW-HHHXNRCGSA-N
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info [1587926]
Cholecystokinin receptor type A Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretionhsa04020:Calcium signaling pathway
Insulin secretion
Pancreatic secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.