Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXH2Q2
|
||||
| Drug Name |
6-Aminomethyl-7-cyclopentyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine
|
||||
| Synonyms |
CHEMBL68082
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H25N5O
|
||||
| Canonical SMILES |
NCc1c(c2ccc(Oc3ccccc3)cc2)c4c(N)ncnc4n1C5CCCC5
|
||||
| InChI |
InChI=1S/C24H25N5O/c25-14-20-21(16-10-12-19(13-11-16)30-18-8-2-1-3-9-18)22-23(26)27-15-28-24(22)29(20)17-6-4-5-7-17/h1-3,8-13,15,17H,4-7,14,25H2,(H2,26,27,28)
|
||||
| InChIKey |
PMZVFSAGPDDIJA-UHFFFAOYSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.