Drug Information
Drug General Information | |||||
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Drug ID |
DXN7M1
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Drug Name |
4-(4-Amino-benzenesulfonylamino)-N-[1-(2S-ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2S-(1-methylcyclopentyl)-ethyl]-benzamide
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Synonyms |
CHEMBL475268
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Indication | Discovery agent | Investigative | [1587926] | ||
Formula |
C28H36N4O6S
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Canonical SMILES |
CC[C@@H]1OCC(=O)[C@H]1NC(=O)[C@H](CC2(C)CCCC2)NC(=O)c3ccc(NS(=O)(=O)c4ccc(N)cc4)cc3
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InChI |
InChI=1S/C28H36N4O6S/c1-3-24-25(23(33)17-38-24)31-27(35)22(16-28(2)14-4-5-15-28)30-26(34)18-6-10-20(11-7-18)32-39(36,37)21-12-8-19(29)9-13-21/h6-13,22,24-25,32H,3-5,14-17,29H2,1-2H3,(H,30,34)(H,31,35)/t22-,24-,25+/m0/s1
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InChIKey |
DWNNWOUIBKMYHH-ZKMPZPQNSA-N
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Target and Pathway | |||||
Target(s) | Cathepsin K | Target Info | [1587926] | ||
Cathepsin L | Target Info | [1587926] | |||
Reactome | Collagen degradation | ||||
Degradation of the extracellular matrix | |||||
Activation of Matrix Metalloproteinases | |||||
Trafficking and processing of endosomal TLR | |||||
MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
Assembly of collagen fibrils and other multimeric structures | |||||
MHC class II antigen presentation | |||||
References |
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