Drug Information

Drug General Information
Drug ID
DXNR5G
Drug Name
N-Benzo[1,3]dioxol-5-ylmethyl-4-(3-bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N'-cyano-piperidine-1-carboxamidine
Synonyms
CHEMBL348280
Indication Discovery agent Investigative [1587926]
Formula
C29H25BrClN5O2
Canonical SMILES
Clc1ccc2C(=C3CCN(CC3)\\C(=N/Cc4ccc5OCOc5c4)\\NC#N)c6ncc(Br)cc6CCc2c1
InChI
InChI=1S/C29H25BrClN5O2/c30-22-12-21-3-2-20-13-23(31)4-5-24(20)27(28(21)33-15-22)19-7-9-36(10-8-19)29(35-16-32)34-14-18-1-6-25-26(11-18)38-17-37-25/h1,4-6,11-13,15H,2-3,7-10,14,17H2,(H,34,35)
InChIKey
LACCMSWGLLPOQN-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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