Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXOS7T
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| Drug Name |
2-cyano-4-(2,2-dimethyl-propylamino)-pyrimidine-5-carboxylic acid {2-[4-(4-methyl-piperazin-1-yl)-phenyl]-ethyl}-amide
|
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| Synonyms |
CHEMBL220760
|
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H33N7O
|
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| Canonical SMILES |
CN1CCN(CC1)c2ccc(CCNC(=O)c3cnc(nc3NCC(C)(C)C)C#N)cc2
|
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| InChI |
InChI=1S/C24H33N7O/c1-24(2,3)17-28-22-20(16-27-21(15-25)29-22)23(32)26-10-9-18-5-7-19(8-6-18)31-13-11-30(4)12-14-31/h5-8,16H,9-14,17H2,1-4H3,(H,26,32)(H,27,28,29)
|
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| InChIKey |
RZGXNMYCQHETTM-UHFFFAOYSA-N
|
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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