Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXP2S2
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| Drug Name |
2-cyano-4-(cyclohexylmethoxy)-N-phenethylpyrimidine-5-carboxamide
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| Synonyms |
CHEMBL463180
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C21H24N4O2
|
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| Canonical SMILES |
O=C(NCCc1ccccc1)c2cnc(nc2OCC3CCCCC3)C#N
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| InChI |
InChI=1S/C21H24N4O2/c22-13-19-24-14-18(20(26)23-12-11-16-7-3-1-4-8-16)21(25-19)27-15-17-9-5-2-6-10-17/h1,3-4,7-8,14,17H,2,5-6,9-12,15H2,(H,23,26)
|
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| InChIKey |
RQFQNQBNKTWWPR-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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