Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXR3H1
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| Drug Name |
N-[1-((S)-(S)-4-Benzoyl-6-(S)-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carbonyl)-3-methyl-butyl]-4-dimethylamino-benzamide
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| Synonyms |
CHEMBL607123
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H34N4O4
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| Canonical SMILES |
CC(C)C[C@H](NC(=O)c1ccc(cc1)N(C)C)C(=O)N2CC[C@@H]3[C@H]2C(=O)CN3C(=O)c4ccccc4
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| InChI |
InChI=1S/C28H34N4O4/c1-18(2)16-22(29-26(34)19-10-12-21(13-11-19)30(3)4)28(36)31-15-14-23-25(31)24(33)17-32(23)27(35)20-8-6-5-7-9-20/h5-13,18,22-23,25H,14-17H2,1-4H3,(H,29,34)/t22-,23+,25-/m0/s1
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| InChIKey |
XVXGIBWJZKQFOS-ARNLJNQMSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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