Drug Information

Drug General Information
Drug ID
DXS0JI
Drug Name
(S)-2-{(4E,8E)-2-[Benzenesulfonyl-(3-methyl-3H-imidazol-4-ylmethyl)-amino]-5,9,13-trimethyl-tetradeca-4,8,12-trienoylamino}-3-phenyl-propionic acid
Synonyms
CHEMBL32600
Indication Discovery agent Investigative [1587926]
Formula
C37H48N4O5S
Canonical SMILES
CC(=CCC\\C(=C\\CC\\C(=C\\CC(N(Cc1cncn1C)S(=O)(=O)c2ccccc2)C(=O)N[C@@H](Cc3ccccc3)C(=O)O)\\C)\\C)C
InChI
InChI=1S/C37H48N4O5S/c1-28(2)14-12-15-29(3)16-13-17-30(4)22-23-35(36(42)39-34(37(43)44)24-31-18-8-6-9-19-31)41(26-32-25-38-27-40(32)5)47(45,46)33-20-10-7-11-21-33/h6-11,14,16,18-22,25,27,34-35H,12-13,15,17,23-24,26H2,1-5H3,(H,39,42)(H,43,44)/b29-16+,30-22+/t34-,35?/m0/s1
InChIKey
KCGKTDGTUPTPRX-ONQYJDIISA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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