Drug Information

Drug General Information
Drug ID
DXT0BN
Drug Name
(R)-5-(4-Benzoyl-piperidin-1-yl)-5-oxo-4-(3-m-tolyl-ureido)-pentanoic acid benzyl ester
Synonyms
CHEMBL103276
Indication Discovery agent Investigative [1587926]
Formula
C32H35N3O5
Canonical SMILES
Cc1cccc(NC(=O)N[C@H](CCC(=O)OCc2ccccc2)C(=O)N3CCC(CC3)C(=O)c4ccccc4)c1
InChI
InChI=1S/C32H35N3O5/c1-23-9-8-14-27(21-23)33-32(39)34-28(15-16-29(36)40-22-24-10-4-2-5-11-24)31(38)35-19-17-26(18-20-35)30(37)25-12-6-3-7-13-25/h2-14,21,26,28H,15-20,22H2,1H3,(H2,33,34,39)/t28-/m1/s1
InChIKey
DUPJRHKBDSHZPG-MUUNZHRXSA-N
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info [1587926]
Cholecystokinin receptor type A Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretionhsa04020:Calcium signaling pathway
Insulin secretion
Pancreatic secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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