Drug Information

Drug General Information
Drug ID
DXT1UR
Drug Name
4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-cyano-N'-phenyl-piperidine-1-carboxamidine
Synonyms
CHEMBL433885
Indication Discovery agent Investigative [1587926]
Formula
C27H24ClN5
Canonical SMILES
Clc1ccc2C(=C3CCN(CC3)\\C(=N/c4ccccc4)\\NC#N)c5ncccc5CCc2c1
InChI
InChI=1S/C27H24ClN5/c28-22-10-11-24-21(17-22)9-8-20-5-4-14-30-26(20)25(24)19-12-15-33(16-13-19)27(31-18-29)32-23-6-2-1-3-7-23/h1-7,10-11,14,17H,8-9,12-13,15-16H2,(H,31,32)
InChIKey
TYPHXBVHOORWLS-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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