Drug Information
| Drug General Information | |||||
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| Drug ID |
DXW2GE
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| Drug Name |
1-(4-chlorophenyl)-3-{19-methyl-14-oxo-3-propyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-7-yl}urea
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| Synonyms |
CHEMBL219581
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C30H27ClN6O2
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| Canonical SMILES |
CCCn1c2ccc(NC(=O)Nc3ccc(Cl)cc3)cc2c4c5CNC(=O)c5c6c(CCc7nn(C)cc67)c14
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| InChI |
InChI=1S/C30H27ClN6O2/c1-3-12-37-24-11-8-18(34-30(39)33-17-6-4-16(31)5-7-17)13-20(24)26-21-14-32-29(38)27(21)25-19(28(26)37)9-10-23-22(25)15-36(2)35-23/h4-8,11,13,15H,3,9-10,12,14H2,1-2H3,(H,32,38)(H2,33,34,39)
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| InChIKey |
DKUYTKHBPXDTOL-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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