Drug Information

Drug General Information
Drug ID
DXY2DK
Drug Name
4-(5-{[3-(3-Chloro-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[d]azepin-1-ylamino]-methyl}-imidazol-1-ylmethyl)-benzonitrile
Synonyms
CHEMBL434879
Indication Discovery agent Investigative [1587926]
Formula
C29H26ClN5O
Canonical SMILES
Clc1cccc(CN2CCc3ccccc3C(NCc4cncn4Cc5ccc(cc5)C#N)C2=O)c1
InChI
InChI=1S/C29H26ClN5O/c30-25-6-3-4-23(14-25)19-34-13-12-24-5-1-2-7-27(24)28(29(34)36)33-17-26-16-32-20-35(26)18-22-10-8-21(15-31)9-11-22/h1-11,14,16,20,28,33H,12-13,17-19H2
InChIKey
JUHFBGZNDZFVMC-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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