Drug Information

Drug General Information
Drug ID
DXZ22A
Drug Name
(17R,20R)-19,20,21,22-Tetrahydro-21-methyl19-oxo-17H-15,17:18,20-diethano-6,10:12,16-dimetheno-16H-imidazo[3,4-h][1,8,11,14]oxatriazacycloeicosine-9-carbonitrile
Synonyms
CHEMBL496065
Indication Discovery agent Investigative [1587926]
Formula
C26H25N5O2
Canonical SMILES
CN1Cc2cncn2Cc3ccc(C#N)c(Oc4ccc5CC[C@@H](N6CC[C@@H]1C6=O)c5c4)c3
InChI
InChI=1S/C26H25N5O2/c1-29-15-20-13-28-16-30(20)14-17-2-3-19(12-27)25(10-17)33-21-6-4-18-5-7-23(22(18)11-21)31-9-8-24(29)26(31)32/h2-4,6,10-11,13,16,23-24H,5,7-9,14-15H2,1H3/t23-,24-/m1/s1
InChIKey
KPRXKFKHZVTBIT-DNQXCXABSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.