Drug Information

Drug General Information
Drug ID
DXZ91D
Drug Name
1-(4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperidin-1-yl]-2-oxo-ethyl}-piperidin-1-yl)-2-pyrrol-1-yl-ethanone
Synonyms
CHEMBL91213
Indication Discovery agent Investigative [1587926]
Formula
C32H35Br2ClN4O2
Canonical SMILES
Clc1cc(Br)c2[C@@H](C3CCN(CC3)C(=O)CC4CCN(CC4)C(=O)Cn5cccc5)c6ncc(Br)cc6CCc2c1
InChI
InChI=1S/C32H35Br2ClN4O2/c33-25-16-24-4-3-23-17-26(35)18-27(34)30(23)31(32(24)36-19-25)22-7-13-38(14-8-22)28(40)15-21-5-11-39(12-6-21)29(41)20-37-9-1-2-10-37/h1-2,9-10,16-19,21-22,31H,3-8,11-15,20H2/t31-/m1/s1
InChIKey
IMLYAVYEFBDHJX-WJOKGBTCSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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