Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| AuroraA --- STK1 | N-(3-fluorophenyl)-2-(2-(7-(3-((2-hydroxyethyl)(prop-2-ynyl)amino)propoxy)-6-methoxyquinazolin-4-ylamino)thiazol-5-yl)acetamide | Drug Info |
| AuroraA --- STK1 | 1-(4-(5-chloro-4-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridin-2-yl)phenyl)-N,N-dimethylmethanamine | Drug Info |
| AuroraA --- STK1 | N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)phenyl)-3-phenoxybenzamide | Drug Info |
| AuroraA --- STK1 | N-(3-(1H-pyrazol-4-yl)-6-(pyridin-3-yl)imidazo[1,2-a]pyrazin-8-yl)-3-methylisothiazol-5-amine | Drug Info |
| AuroraA --- STK1 | 1-(3-(pyrrolidin-1-ylmethyl)-5-(trifluoromethyl)phenyl)-3-(5-(2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl)thiazol-2-yl)urea | Drug Info |
| AuroraA --- STK1 | 1,1-Dimethylethyl{(3R,5R)-1-[2-Amino-6-(3-amino-1H-indazol-6-yl)-4-pyrimidinyl]-5-methyl-3-piperidinyl}methylcarbamate | Drug Info |
| AuroraA --- STK1 | (Z)-3-({3-[3-(Dimethylamino)propyl]-4-oxo-4,5,6,7-tetrahydro-1H-indol-2-yl}methylene)-5-(indolin-1-ylsulfonyl)indolin-2-one | Drug Info |
| AuroraA --- STK1 | 3-methyl-5-(4-methyl-3-(3-((4-methylpiperazin-1-yl)methyl)styryl)-1H-indazol-5-yl)aniline | Drug Info |
| AuroraA --- STK1 | N-(4-(4-methyl-6-(5-methyl-1H-pyrazol-3-ylamino)pyrimidin-2-ylthio)phenyl)propionamide | Drug Info |
| AuroraA --- STK1 | N-(4-(6-(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-2-ylamino)phenethyl)thieno[3,2-d]pyrimidin-4-amine | Drug Info |
| AuroraA --- STK1 | N-(3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)-3-methylisothiazol-5-amine | Drug Info |
| AuroraA --- STK1 | N-2,3-difluorophenyl-2-3-7-3-4-2-hydroxyethyl-piperazin-1-yl-propoxy-6-methoxyquinazolin-4-ylamino-1H-pyrazol-5-yl-acetamide | Drug Info |
| AuroraA --- STK1 | 4-[3-(4-N-Phenylcarbamylaminophenyl)-1-ethyl-1H-pyrazol-4-yl]-2-[4-(dimethylaminomethyl)phenyl]-1H-pyrrolo[2,3-b]pyridine | Drug Info |
| AuroraA --- STK1 | 2-{2-[(7-{3-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]propoxy}-6-methoxyquinazolin-4-yl)amino]-1,3-thiazol-5-yl}-N-(3-methoxyphenyl)acetamide | Drug Info |
| AuroraA --- STK1 | 1-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)-3-(tetrahydro-2H-pyran-4-yl)urea | Drug Info |
| AuroraA --- STK1 | 3-(1-methyl-1H-pyrazol-4-yl)-N-(4-methylthiophen-2-yl)imidazo[1,2-a]pyrazin-8-amine | Drug Info |
| AuroraA --- STK1 | N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)-3-((4-(methylsulfonyl)piperazin-1-yl)methyl)isothiazol-5-amine | Drug Info |
| AuroraA --- STK1 | N-(3-(1H-pyrazol-4-yl)-6-(trifluoromethyl)imidazo[1,2-a]pyrazin-8-yl)-3-methylisothiazol-5-amine | Drug Info |
| AuroraA --- STK1 | N-(3-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)-3-(piperidin-4-yl)isothiazol-5-amine | Drug Info |
| AuroraA --- STK1 | (Z)-5-(Indolin-1-ylsulfonyl)-3-{[3-(3-morpholino-3-oxopropyl)-4-oxo-4,5,6,7-tetrahydro-1H-indol-2-yl]methylene}indolin-2-one | Drug Info |
| AuroraA --- STK1 | N-(6-(ethylthio)-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)-3-methylisothiazol-5-amine | Drug Info |
| AuroraA --- STK1 | 2-(2-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinazolin-4-yl]amino}-1,3-thiazol-5-yl)-N-(3-methylbutyl)acetamide | Drug Info |
| AuroraA --- STK1 | 5-(6-methoxy-7-(3-morpholinopropoxy)quinazolin-4-ylamino)-N-phenylthiophene-2-carboxamide | Drug Info |
| AuroraA --- STK1 | 3-(8-oxa-5-azaspiro[3.5]nonan-5-ylmethyl)-N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)isothiazol-5-amine | Drug Info |
| AuroraA --- STK1 | PHA-680632 | Drug Info |
| AuroraA --- STK1 | 1-phenyl-3-(5-(2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl)thiazol-2-yl)urea | Drug Info |
| AuroraA --- STK1 | N-(3-fluorophenyl)-2-{2-[(7-{3-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]propoxy}-6-methoxyquinazolin-4-yl)amino]-1,3-thiazol-5-yl}acetamide | Drug Info |
| AuroraA --- STK1 | 2-[3-(4-{[(Phenylamino)carbonyl]amino}phenyl)-4-(1H-pyrrolo-[2,3-b]pyridin-4-yl)-1H-pyrazol-1-yl]acetamide | Drug Info |
| AuroraA --- STK1 | 1-(4-((5-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-ylamino)isothiazol-3-yl)methyl)piperazin-1-yl)ethanone | Drug Info |
| AuroraA --- STK1 | 5-Ethyl-7,7-dimethyl-2-(5-methyl-1H-pyrazol-3-yl)-6-oxo-1Himidazo[4,5-f]indole | Drug Info |
| AuroraA --- STK1 | CHEMBL424899 | Drug Info |
| AuroraA --- STK1 | N-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrimidin-2-ylthio)phenyl)acetamide | Drug Info |
| AuroraA --- STK1 | N-(6-(2-(dimethylamino)ethylthio)-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)-3-methylisothiazol-5-amine | Drug Info |
| AuroraA --- STK1 | 1-(1H-indol-7-yl)-3-(5-(2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl)thiazol-2-yl)urea | Drug Info |
| AuroraA --- STK1 | 4-methyl-3-(3-((4-methylpiperazin-1-yl)methyl)styryl)-1H-indazole-5-carbonitrile | Drug Info |
| AuroraA --- STK1 | MLN-8054 | Drug Info |
| AuroraA --- STK1 | N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)-3-(pyrrolidin-1-ylmethyl)isothiazol-5-amine Hydrochloride | Drug Info |
| AuroraA --- STK1 | N-(2-(2-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-ylamino)thiazol-5-yl)ethyl)thieno[3,2-d]pyrimidin-4-amine | Drug Info |
| AuroraA --- STK1 | CHEMBL214849 | Drug Info |
| AuroraA --- STK1 | 1-(3-fluorophenyl)-3-(5-(2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl)thiazol-2-yl)urea | Drug Info |
| AuroraA --- STK1 | 2-Chloro-N-(4-(5-fluoro-2-(4-hydroxyphenylamino)pyrimidin-4-ylamino)phenyl)benzamide | Drug Info |
| AuroraA --- STK1 | CHEMBL214848 | Drug Info |
| AuroraA --- STK1 | [1-(3-{[4-({5-[(3-fluorobenzyl)thio]-1,3-thiazol-2-yl}amino)-6-methoxyquinazolin-7-yl]oxy}propyl)piperidin-4-yl]methanol | Drug Info |
| AuroraA --- STK1 | 2-(4-((5-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-ylamino)isothiazol-3-yl)methyl)piperazin-1-yl)ethanol | Drug Info |
| AuroraA --- STK1 | (2S,5R)-4-[2-Amino-6-(3-amino-1H-indazol-6-yl)-4-pyrimidinyl]-5-methyl-N-phenyl-2-morpholinecarboxamide | Drug Info |
| AuroraA --- STK1 | (+/-)-N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)-3-(morpholino(pyridin-2-yl)methyl)isothiazol-5-amine | Drug Info |
| AuroraA --- STK1 | N-(4-{1-Ethyl-4-[2-({[2-(methylsulfonyl)ethyl]amino}methyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-1H-pyrazol-3-yl}phenyl)-N'-phenylurea | Drug Info |
| AuroraA --- STK1 | CHEMBL201197 | Drug Info |
| AuroraA --- STK1 | N-(3-fluorophenyl)-2-(2-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinazolin-4-yl]amino}-1,3-oxazol-5-yl)acetamide | Drug Info |
| AuroraA --- STK1 | N-[3-[(3(S)-Fluoro-1-pyrrolidinyl)methyl]-5-isothiazolyl]-6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine Hydrochloride | Drug Info |
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