Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CDK4 --- Cyclin E | 1-{3-[5-([1,4]Diazepane-1-carbonyl)-thiophen-2-yl]-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl}-3-morpholin-4-yl-urea | Drug Info |
| CDK4 --- Cyclin E | 5-[5-(3-Morpholin-4-yl-ureido)-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-3-yl]-thiophene-2-carboxylic acid (2-pyrrolidin-1-yl-ethyl)-amide | Drug Info |
| CDK4 --- Cyclin E | 1-{3-[5-(4-Methyl-[1,4]diazepane-1-carbonyl)-thiophen-2-yl]-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl}-3-morpholin-4-yl-urea | Drug Info |
| CDK4 --- Cyclin E | 1-{3-[5-(3-Amino-pyrrolidine-1-carbonyl)-thiophen-2-yl]-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl}-3-morpholin-4-yl-urea | Drug Info |
| CDK4 --- Cyclin E | 1-{3-[5-(3-Methylamino-pyrrolidine-1-carbonyl)-thiophen-2-yl]-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl}-3-morpholin-4-yl-urea | Drug Info |
| CDK4 --- Cyclin E | N-[3-(5-chlorothien-3-yl)-4-oxo-2,4-dihydroindeno[1,2-c]pyrazol-5-yl]-2,2-dimethylhydrazinecarboxamide | Drug Info |
| CDK4 --- Cyclin E | N-[3-(2-furyl)-4-oxo-2,4-dihydroindeno[1,2-c]pyrazol-5-yl]-2,2-dimethylhydrazinecarboxamide | Drug Info |
| CDK4 --- Cyclin E | 2,2-dimethyl-N-[3-(5-methylthien-2-yl)-4-oxo-2,4-dihydroindeno[1,2-c]pyrazol-5-yl]hydrazinecarboxamide | Drug Info |
| CDK4 --- Cyclin E | 1-{3-[5-(4-Ethyl-piperazine-1-carbonyl)-thiophen-2-yl]-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl}-3-morpholin-4-yl-urea | Drug Info |
| CDK4 --- Cyclin E | N-[3-(2,4-dimethyl-1,3-thiazol-5-yl)-4-oxo-2,4-dihydroindeno[1,2-c]pyrazol-5-yl]-2,2-dimethylhydrazinecarboxamide | Drug Info |
| CDK4 --- Cyclin E | 1-{3-[5-(4-Dimethylamino-piperidine-1-carbonyl)-thiophen-2-yl]-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl}-3-morpholin-4-yl-urea | Drug Info |
| CDK4 --- Cyclin E | 5-{5-[3-(4-Methyl-piperazin-1-yl)-ureido]-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-3-yl}-thiophene-2-carboxylic acid ethyl ester | Drug Info |
| CDK4 --- Cyclin E | 5-[5-(3-Morpholin-4-yl-ureido)-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-3-yl]-thiophene-2-carboxylic acid (2-dimethylamino-ethyl)-amide | Drug Info |
| CDK4 --- Cyclin E | N-[3-(5-methoxythien-2-yl)-4-oxo-2,4-dihydroindeno[1,2-c]pyrazol-5-yl]-2,2-dimethylhydrazinecarboxamide | Drug Info |
| CDK4 --- Cyclin E | 1-[3-(5-Methyl-thiophen-2-yl)-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl]-3-morpholin-4-yl-urea | Drug Info |
| CDK4 --- Cyclin E | 1-[3-(2,5-Dimethyl-thiophen-3-yl)-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl]-3-(4-methyl-piperazin-1-yl)-urea | Drug Info |
| CDK4 --- Cyclin E | 1-[3-(2,4-Dimethyl-thiazol-5-yl)-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl]-3-morpholin-4-yl-urea | Drug Info |
| CDK4 --- Cyclin E | 2,2-dimethyl-N-(4-oxo-3-thien-2-yl-2,4-dihydroindeno[1,2-c]pyrazol-5-yl)hydrazinecarboxamide | Drug Info |
| CDK4 --- Cyclin E | 1-{3-[5-(3-Dimethylamino-piperidine-1-carbonyl)-thiophen-2-yl]-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl}-3-morpholin-4-yl-urea | Drug Info |
| CDK4 --- Cyclin E | 1-{3-[5-(Azepane-1-carbonyl)-thiophen-2-yl]-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl}-3-morpholin-4-yl-urea | Drug Info |
| CDK4 --- Cyclin E | ethyl 5-(5-{[(2,2-dimethylhydrazino)carbonyl]amino}-4-oxo-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)thiophene-2-carboxylate | Drug Info |
| CDK4 --- Cyclin E | 5-[5-(3-Morpholin-4-yl-ureido)-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-3-yl]-thiophene-2-carboxylic acid ethyl ester | Drug Info |
| CDK4 --- Cyclin E | 1-{3-[5-(3-Dimethylamino-pyrrolidine-1-carbonyl)-thiophen-2-yl]-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl}-3-morpholin-4-yl-urea | Drug Info |
| CDK4 --- Cyclin E | 1-[3-(5-Chloro-thiophen-3-yl)-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl]-3-morpholin-4-yl-urea | Drug Info |
| CDK4 --- Cyclin E | 1-Morpholin-4-yl-3-{4-oxo-3-[5-(piperidine-1-carbonyl)-thiophen-2-yl]-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl}-urea | Drug Info |
| CDK4 --- Cyclin E | 1-Morpholin-4-yl-3-{4-oxo-3-[5-(piperazine-1-carbonyl)-thiophen-2-yl]-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl}-urea | Drug Info |
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