Resistance mutation info of drug

Drug General Information
Drug ID D0MU7U
Drug Name Carbamates Drug Info
Drug Resistance Mutations
Target Name Culex pipiens Acetylcholinestrerase (Ace1)
Gene Name ace1
Uniprot ID Q86CZ4_TETUR
Species Tetranychus urticae
Reference Sequence MVPMFNHNINHFNNVIVTTLTHHQYTNSRCNSNNNVIKRITNSILKSVTVFTVKTLWNHL
LVPIVVILLFQSSANVFSSALPHSEINSFHADGPSSSSSFNSEHHHHHHHNDPLVVLTKK
GYVRGRSVVSPTGKPVDAFLGIRYAKPPTGKFRFRHPKPIDSWQGIFNATSFSGACYQVN
DTFFGNFMGATEWNPNVPLDEDCLSVNIWVPRPRPKSAAVLLWIYGGSFWSGSSSLDFYD
GSVLAGEESIIFVSINYRVASLGFIFFDTSDAPGNAGLFDQLMAMEWIRENIAAFGGNPA
NITIFGESAGAVSAALHLLSPLSRNVFSQAILQSGSATCPWAISDRKKAYQRSLALAQAV
GCGSTSTRSVHAIIECMQSIPASELVAQEETTTGVVEFAFIPIVDGSFLDEDPEVSLRTK
NFKHTPILTGSNRDEGTYFLVYHSPHIFNLSEGIYISRSEFQSLIRIIYPHLSPLAQEAV
IQEYTHWINPDDQIENREATDKFVGDYHFTCPVNEMSYRYALYGNDVWTYHFTHRSSKSF
WPSWMGVIHGEEIKFVLGEPLDPVHGYTPAEVQLSKRIMRYWANFARTGNPNKQFPDGDD
TESIVWPEYTAHEKEYLVISTNDSSIGRGLRAKQCAFWKNFLPKLINALENRHNSTCTSH
SNQIGSSNWSLAISLISLIMCFLPSLR [Tetranychus urticae]
Targeted Disease Propagation of disease by mosquito
Drug Resistance Mutations
Mutation info Missense: G119S [1559246]
Mutation info Missense: A201S [1559246]
Mutation info Missense: F331W [1559246]
Mutation info Missense: F331Y [1559246]
Mutation info Missense: G328A [1559246]
Mutation info Missense: T280A [1559246]
References
Ref 1572595Capecitabine, an oral fluoropyrimidine carbamate with substantial activity in advanced colorectal cancer: results of a randomized phase II study.
Ref 1559246Global distribution and origin of target site insecticide resistance mutations in Tetranychus urticae.Insect Biochem Mol Biol.2014 May;48:17-28.

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